Endocrine Abstracts

Experimental autoimmune thyroiditis (EAT) has been used to simulate human autoimmune thyroid disease for decades. EAT can be easily induced in genetically susceptible strains of mice by excess iodine ingestion or by immunization with mouse thyroglobulin. Excess iodine may induce and exacerbate autoimmune thyroiditis (AIT) in humans and animal models. In order to assess the potential protective mechanisms of selenium (Se) in thyroid autoimmunity, we evaluated the effects of ino...